Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans

Epidemiological, genetic association, and Mendelian randomization studies have provided strong evidence that lipoprotein (a) [Lp(a)] is an independent causal risk factor for CVD, including myocardial infarction, stroke, peripheral arterial disease, and calcific aortic valve stenosis. Lp(a) levels &g...

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Bibliographic Details
Main Authors: Mark J. Graham, Nick Viney, Rosanne M. Crooke, Sotirios Tsimikas
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752035433X