Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

Coronavirus disease 2019 (COVID-19) shows a wide variation in expression and severity of symptoms, from very mild or no symptoms, to flu-like symptoms, and in more severe cases, to pneumonia, acute respiratory distress syndrome, and even death. Large differences in outcome have also been observed be...

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Bibliographic Details
Main Authors: Esteban A. Lopera Maya, Adriaan van der Graaf, Pauline Lanting, Marije van der Geest, Jingyuan Fu, Morris Swertz, Lude Franke, Cisca Wijmenga, Patrick Deelen, Alexandra Zhernakova, Serena Sanna, Lifelines Cohort Study
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
PheWAS
ACE2
TMPRSS2
NSAIDs (non-steroidal anti-inflammatory drugs)
ARBs (angiotensin II receptor blockers)
COVID-19
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00613/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00613/full

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