Detection of EGFR Activating and Resistance Mutations by Droplet Digital PCR in Sputum of EGFR-Mutated NSCLC Patients

Detection of EGFR Activating and Resistance Mutations by Droplet Digital PCR in Sputum of EGFR-Mutated NSCLC Patients

Background: Proof of the T790M resistance mutation is mandatory if patients with EGFR -mutated non-small cell lung cancer (NSCLC) progress under first- or second-generation tyrosine kinase inhibitor therapy. In addition to rebiopsy, analysis of plasma circulating tumor DNA is used to detect T790M re...

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Bibliographic Details
Main Authors: Klaus Hackner, Anna Buder, Maximilian J Hochmair, Matthaeus Strieder, Christina Grech, Hannah Fabikan, Otto C. Burghuber, Peter Errhalt, Martin Filipits
Format: Article
Language:English
Published: SAGE Publishing 2021-02-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.1177/1179554921993072

Internet

https://doi.org/10.1177/1179554921993072

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