Quantitative definition of neurobehavior, vision, hearing and brain volumes in macaques congenitally exposed to Zika virus.

Quantitative definition of neurobehavior, vision, hearing and brain volumes in macaques congenitally exposed to Zika virus.

Congenital Zika virus (ZIKV) exposure results in a spectrum of disease ranging from severe birth defects to delayed onset neurodevelopmental deficits. ZIKV-related neuropathogenesis, predictors of birth defects, and neurodevelopmental deficits are not well defined in people. Here we assess the metho...

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Main Authors: Michelle R Koenig, Elaina Razo, Ann Mitzey, Christina M Newman, Dawn M Dudley, Meghan E Breitbach, Matthew R Semler, Laurel M Stewart, Andrea M Weiler, Sierra Rybarczyk, Kathryn M Bach, Mariel S Mohns, Heather A Simmons, Andres Mejia, Michael Fritsch, Maria Dennis, Leandro B C Teixeira, Michele L Schotzko, T Michael Nork, Carol A Rasmussen, Alex Katz, Veena Nair, Jiancheng Hou, Amy Hartman, James Ver Hoeve, Charlene Kim, Mary L Schneider, Karla Ausderau, Sarah Kohn, Anna S Jaeger, Matthew T Aliota, Jennifer M Hayes, Nancy Schultz-Darken, Jens Eickhoff, Kathleen M Antony, Kevin Noguchi, Xiankun Zeng, Sallie Permar, Vivek Prabhakaran, Saverio Capuano, Thomas C Friedrich, Thaddeus G Golos, David H O'Connor, Emma L Mohr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235877

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https://doi.org/10.1371/journal.pone.0235877

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