High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors

High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors

<p>Abstract</p> <p>Background</p> <p>To mimic clinical treatment situations in advanced human ovarian disease, we tested the efficacy of CpG-oligodeoxynucleotides (CpG-ODN), synthetic DNA sequences recognized by Toll-like receptor 9 and able to induce innate/adaptive im...

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Bibliographic Details
Main Authors: Sommariva Michele, de Cesare Michelandrea, Meini Alessandra, Cataldo Alessandra, Zaffaroni Nadia, Tagliabue Elda, Balsari Andrea
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Journal of Translational Medicine
Subjects:
CpG-ODN
TLR9
Ovarian cancer
Ascites
Monoclonal Antibody
Cisplatin
Online Access:http://www.translational-medicine.com/content/11/1/25

Internet

http://www.translational-medicine.com/content/11/1/25

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