Genetic basis of index patients with familial hypercholesterolemia in Chinese population: mutation spectrum and genotype-phenotype correlation

Genetic basis of index patients with familial hypercholesterolemia in Chinese population: mutation spectrum and genotype-phenotype correlation

Abstract Background Although there have been many reports in the genetics of familial hypercholesterolemia (FH) worldwide, studies in regard of Chinese population are lacking. In this multi-center study, we aim to characterize the genetic spectrum of FH in Chinese population, and examine the genotyp...

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Bibliographic Details
Main Authors: Di Sun, Bing-Yang Zhou, Sha Li, Ning-Ling Sun, Qi Hua, Shu-Lin Wu, Yun-Shan Cao, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Ying Gao, Chuan-Jue Cui, Geng Liu, Jian-Jun Li
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Lipids in Health and Disease
Subjects:
Familial hypercholesterolemia
Lipid
LDLR
APOB
PCSK9
Online Access:http://link.springer.com/article/10.1186/s12944-018-0900-8

Internet

http://link.springer.com/article/10.1186/s12944-018-0900-8

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