Role of CD14 in host protection against infections and in metabolism regulation

CD14 is a glycosylphosphatidylinositol (GPI)-anchored receptor known to serve as a co-receptor for several Toll-like Receptors (TLRs) both at the cell surface and in the endosomal compartment. CD14 can be expressed by cells of both hematopoietic and non-hematopoietic origin as a cell membrane or sec...

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Bibliographic Details
Main Authors: Francesca eGranucci, Ivan eZanoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00032/full