A Biodegradable Copolyester, Poly(butylene succinate-<i>co</i>-ε-caprolactone), as a High Efficiency Matrix Former for Controlled Release of Drugs

A Biodegradable Copolyester, Poly(butylene succinate-<i>co</i>-ε-caprolactone), as a High Efficiency Matrix Former for Controlled Release of Drugs

A biodegradable copolyester, poly(butylene succinate-<i>co</i>-ε-caprolactone) (PBS_CL), was used for first time as an excipient for pharmaceutical dosage forms using direct compression and hot processing techniques (ultrasound-assisted compression (USAC) and hot melt extrusion (HME)). R...

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Bibliographic Details
Main Authors: Eduardo Galdón, Mónica Millán-Jiménez, Gloria Mora-Castaño, Antxon Martínez de Ilarduya, Isidoro Caraballo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
poly(butylene succinate-<i>co</i>-ε-caprolactone)
biodegradable polymer
ultrasound-assisted compression
hot melt extrusion
controlled release
nanostructured matrices
Online Access:https://www.mdpi.com/1999-4923/13/7/1057

Internet

https://www.mdpi.com/1999-4923/13/7/1057

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