RRM2B-Mediated Regulation of Mitochondrial Activity and Inflammation under Oxidative Stress

RRM2B is a critical ribonucleotide reductase (RR) subunit that exists as p53-inducible and p53-dependent molecule. The p53-independent regulation of RRM2B has been recently studied, and FOXO3 was identified as a novel regulator of RRM2B. However, the p53-independent regulation of RRM2B, particularl...

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Bibliographic Details
Main Authors: Er-Chieh Cho, Mei-Ling Kuo, Jia-hui Cheng, Yu-Chi Cheng, Yi-Chen Hsieh, Yun-Ru Liu, Rong-Hong Hsieh, Yun Yen
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/287345