A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes

A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes

Abstract Fibroblast-like synoviocytes (FLS) play a pathogenic role in rheumatoid arthritis (RA). STAT3 signaling is activated in FLS of RA patients (RA-FLS), which in turn causes RA-FLS hyperproliferation. RL is a traditional remedy for treating inflammatory diseases in China. It comprises Rosae Mul...

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Bibliographic Details
Main Authors: Ying-Jie Chen, Yu-Xi Liu, Jia-Ying Wu, Chun-Yu Li, Min-Min Tang, Lu Bai, Xiu-Qiong Fu, Jun-Kui Li, Ji-Yao Chou, Cheng-Le Yin, Ya-Ping Wang, Jing-Xuan Bai, Ying Wu, Xiao-Qi Wang, Zhi-Ling Yu
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83435-2

Internet

https://doi.org/10.1038/s41598-021-83435-2

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