integRATE: a desirability-based data integration framework for the prioritization of candidate genes across heterogeneous omics and its application to preterm birth

integRATE: a desirability-based data integration framework for the prioritization of candidate genes across heterogeneous omics and its application to preterm birth

Abstract Background The integration of high-quality, genome-wide analyses offers a robust approach to elucidating genetic factors involved in complex human diseases. Even though several methods exist to integrate heterogeneous omics data, most biologists still manually select candidate genes by exam...

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Bibliographic Details
Main Authors: Haley R. Eidem, Jacob L. Steenwyk, Jennifer H. Wisecaver, John A. Capra, Patrick Abbot, Antonis Rokas
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Medical Genomics
Subjects:
Prematurity
Integrative genomics
Complex disease
Candidate gene ranking
Venn diagram
Online Access:http://link.springer.com/article/10.1186/s12920-018-0426-y

Internet

http://link.springer.com/article/10.1186/s12920-018-0426-y

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