Tetracycline inhibits local inflammation induced by cerebral ischemia via modulating autophagy.

Tetracycline exerts neuroprotection via suppressing the local inflammation induced by cerebral ischemia. However, the underlying mechanism is not completely clear.The mRNA and protein expressions of tumor necrosis factor α and interleukin 6 and the number of activated microglia were measured to dete...

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Bibliographic Details
Main Authors: Yongjun Jiang, Juehua Zhu, Li Wu, Gelin Xu, Jianwu Dai, Xinfeng Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492486?pdf=render