8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway

8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway

8-Chloro-adenosine (8-Cl-Ado) has been shown to exhibit its antitumor activity by inducing apoptosis in human lung cancer A549 and H1299 cells or autophagy in chronic lymphocytic leukemia, and MDA-MB-231 and MCF-7 breast cancer cells. Adenosine deaminases acting on RNA 1 (ADAR1) is tightly associate...

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Bibliographic Details
Main Authors: Hong-Yue Ding, Wan-Yong Yang, Li-Hong Zhang, Li Li, Feng Xie, Hua-Yi Li, Xiao-Yu Chen, Zeng Tu, Yi Li, Yong Chen, Sheng-Yong Yang
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720958656

Internet

https://doi.org/10.1177/0963689720958656

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