Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Gradients of morphogens such as Wnt provide instructive cues for cell identities during development. Here, the authors report that in the developing zebrafish embryo, cell competition and elimination of unfit cells are required for proper Wnt gradient formation.

Bibliographic Details
Main Authors: Yuki Akieda, Shohei Ogamino, Hironobu Furuie, Shizuka Ishitani, Ryutaro Akiyoshi, Jumpei Nogami, Takamasa Masuda, Nobuyuki Shimizu, Yasuyuki Ohkawa, Tohru Ishitani
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12609-4

Internet

https://doi.org/10.1038/s41467-019-12609-4

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