Immunological and genetic kinetics from diagnosis to clinical progression in chronic lymphocytic leukemia

Immunological and genetic kinetics from diagnosis to clinical progression in chronic lymphocytic leukemia

Abstract Background Mechanisms driving the progression of chronic lymphocytic leukemia (CLL) from its early stages are not fully understood. The acquisition of molecular changes at the time of progression has been observed in a small fraction of patients, suggesting that CLL progression is not mainl...

Full description

Bibliographic Details
Main Authors: Isabel Jiménez, Bárbara Tazón-Vega, Pau Abrisqueta, Juan C. Nieto, Sabela Bobillo, Carles Palacio-García, Júlia Carabia, Rafael Valdés-Mas, Magdalena Munuera, Lluís Puigdefàbregas, Genís Parra, Anna Esteve-Codina, Clara Franco-Jarava, Gloria Iacoboni, María José Terol, José Antonio García-Marco, Marta Crespo, Francesc Bosch
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biomarker Research
Subjects:
CLL
Immune evasion
Clinical progression
T cell exhaustion
Online Access:https://doi.org/10.1186/s40364-021-00290-z

Internet

https://doi.org/10.1186/s40364-021-00290-z

Similar Items