Human Mesenchymal Stem Cells Retain Multilineage Differentiation Capacity Including Neural Marker Expression after Extended In Vitro Expansion.

The suitability of human mesenchymal stem cells (hMSCs) in regenerative medicine relies on retention of their proliferative expansion potential in conjunction with the ability to differentiate toward multiple lineages. Successful utilisation of these cells in clinical applications linked to tissue r...

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Bibliographic Details
Main Authors: Rachel K Okolicsanyi, Emily T Camilleri, Lotta E Oikari, Chieh Yu, Simon M Cool, Andre J van Wijnen, Lyn R Griffiths, Larisa M Haupt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0137255