Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Abstract Background Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for malaria, despite this, there are no HDAC inhibitors in clinical tri...

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Bibliographic Details
Main Authors: Vijay Potluri, Radha K. Shandil, R. Gavara, Ganesh Sambasivam, Brice Campo, Sergio Wittlin, Shridhar Narayanan
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Histone deacetyl
Online Access:http://link.springer.com/article/10.1186/s12936-020-03421-3

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http://link.springer.com/article/10.1186/s12936-020-03421-3

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