Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria
Abstract Background Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for malaria, despite this, there are no HDAC inhibitors in clinical tri...
Main Authors: | Vijay Potluri, Radha K. Shandil, R. Gavara, Ganesh Sambasivam, Brice Campo, Sergio Wittlin, Shridhar Narayanan |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | Malaria Journal |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12936-020-03421-3 |
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