High yield production process for Shigella outer membrane particles.

Gram-negative bacteria naturally shed particles that consist of outer membrane lipids, outer membrane proteins, and soluble periplasmic components. These particles have been proposed for use as vaccines but the yield has been problematic. We developed a high yielding production process of geneticall...

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Bibliographic Details
Main Authors: Francesco Berlanda Scorza, Anna Maria Colucci, Luana Maggiore, Silvia Sanzone, Omar Rossi, Ilaria Ferlenghi, Isabella Pesce, Mariaelena Caboni, Nathalie Norais, Vito Di Cioccio, Allan Saul, Christiane Gerke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368891?pdf=render