Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma.

Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma.

The presence of stem cell characteristics in glioma cells raises the possibility that mechanisms promoting the maintenance and self-renewal of tissue specific stem cells have a similar function in tumor cells. Here we characterized human gliomas of various malignancy grades for the expression of ste...

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Bibliographic Details
Main Authors: Johan Holmberg, Xiaobing He, Inti Peredo, Abiel Orrego, Göran Hesselager, Christer Ericsson, Outi Hovatta, Sueli Mieko Oba-Shinjo, Suely Kazue Nagahashi Marie, Monica Nistér, Jonas Muhr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069091?pdf=render

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http://europepmc.org/articles/PMC3069091?pdf=render

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