Extensive Placental Methylation Profiling in Normal Pregnancies

Extensive Placental Methylation Profiling in Normal Pregnancies

The placental methylation pattern is crucial for the regulation of genes involved in trophoblast invasion and placental development, both key events for fetal growth. We investigated LINE-1 methylation and methylome profiling using a methylation EPIC array and the targeted methylation sequencing of...

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Bibliographic Details
Main Authors: Ornella Rondinone, Alessio Murgia, Jole Costanza, Silvia Tabano, Margherita Camanni, Luigi Corsaro, Laura Fontana, Patrizia Colapietro, Luciano Calzari, Silvia Motta, Carlo Santaniello, Tatjana Radaelli, Enrico Ferrazzi, Silvano Bosari, Davide Gentilini, Silvia Maria Sirchia, Monica Miozzo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
placenta
methylome
LINE-1
birth weight
normal pregnancies
Online Access:https://www.mdpi.com/1422-0067/22/4/2136

Internet

https://www.mdpi.com/1422-0067/22/4/2136

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