Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure

Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure

Abstract Background Randomized controlled trials in orthopaedics are powered to mainly find large effect sizes. A possible discrepancy between the estimated and the real mean difference is a challenge for statistical inference based on p-values. We explored the justifications of the mean difference...

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Bibliographic Details
Main Authors: Lauri Raittio, Antti Launonen, Ville M. Mattila, Aleksi Reito
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medical Research Methodology
Subjects:
Sample size
Uncertainty
Randomized Controlled Trials as Topic
Orthopaedics
Confidence intervals
Patient reported Outcome measures
Online Access:https://doi.org/10.1186/s12874-021-01249-2

Internet

https://doi.org/10.1186/s12874-021-01249-2

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