High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats.

High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats.

High dietary sodium aggravates renal disease by affecting blood pressure and by its recently shown pro-inflammatory and pro-fibrotic effects. Moreover, pro-inflammatory modification of renal heparan sulfate (HS) can induce tissue remodeling. We aim to investigate if high sodium intake in normotensiv...

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Bibliographic Details
Main Authors: Ryanne S Hijmans, Pragyi Shrestha, Kwaku A Sarpong, Saleh Yazdani, Rana El Masri, Wilhelmina H A de Jong, Gerjan Navis, Romain R Vivès, Jacob van den Born
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5464595?pdf=render

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http://europepmc.org/articles/PMC5464595?pdf=render

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