Interaction of Mannose-Binding Lectin With Lipopolysaccharide Outer Core Region and Its Biological Consequences

Interaction of Mannose-Binding Lectin With Lipopolysaccharide Outer Core Region and Its Biological Consequences

Lipopolysaccharide (LPS, endotoxin), the main surface antigen and virulence factor of Gram-negative bacteria, is composed of lipid A, core oligosaccharide, and O-specific polysaccharide (O-PS) regions. Each LPS region is capable of complement activation. We have demonstrated that LPS of Hafnia alvei...

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Bibliographic Details
Main Authors: Aleksandra Man-Kupisinska, Anna S. Swierzko, Anna Maciejewska, Monika Hoc, Antoni Rozalski, Malgorzata Siwinska, Czeslaw Lugowski, Maciej Cedzynski, Jolanta Lukasiewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
lipopolysaccharide
endotoxin
anaphylactoid shock
complement
mannose-binding lectin
Hafnia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01498/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01498/full

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