Does Angiotensin (1-7) Contribute to the Antiproteinuric Effect of ACE-inhibitors?

Angiotensin-converting enzyme inhibitors (ACE-I) reduce proteinuria and protect the kidney in proteinuric renal disease. During ACE-I therapy, circulating levels of angiotensin (1-7) [Ang (1-7)] are increased. As cardiac and renal protective effects of Ang (1-7) have been reported, we questioned whe...

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Bibliographic Details
Main Authors: Els A van der Wouden, Robert H Henning, Leo E Deelman, Anton JM Roks, Frans Boomsma, Dick de Zeeuw
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2005-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2005.016