TP53 mutation and MET amplification in circulating tumor DNA analysis predict disease progression in patients with advanced gastric cancer

Background Gastric cancer (GC) is a heterogeneous disease that encompasses various molecular subtypes. The molecular mutation characteristics of circulating tumor DNA (ctDNA) in advanced gastric cancer (AGC), especially the clinical utility of TP53 mutation and MET amplification in ctDNA need to be...

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Bibliographic Details
Main Authors: Jia Li, Zhaoyan Li, Yajie Ding, Yan Xu, Xiaohong Zhu, Nida Cao, Chen Huang, Mengmeng Qin, Feng Liu, Aiguang Zhao
Format: Article
Language:English
Published: PeerJ Inc. 2021-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/11146.pdf