Novel expression vectors enabling induction of gene expression by small-interfering RNAs and microRNAs.

Small-interfering RNAs and microRNAs are small ∼21-22 nucleotide long RNAs capable of posttranscriptional suppression of gene expression. The synthetic siRNAs are especially designed to target pre-specified genes and are common molecular biology tools. The miRNAs are endogenous regulators of gene ex...

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Bibliographic Details
Main Authors: Liraz Harel, Nir Gefen, Ofira Carmi, Pini Orbach, Paz Einat, Guy Abitbol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4267845?pdf=render