Transcriptome Analysis of Individual Stromal Cell Populations Identifies Stroma-Tumor Crosstalk in Mouse Lung Cancer Model

Transcriptome Analysis of Individual Stromal Cell Populations Identifies Stroma-Tumor Crosstalk in Mouse Lung Cancer Model

Emerging studies have begun to demonstrate that reprogrammed stromal cells play pivotal roles in tumor growth, metastasis, and resistance to therapy. However, the contribution of stromal cells to non-small-cell lung cancer (NSCLC) has remained underexplored. We used an orthotopic model of Kras-drive...

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Bibliographic Details
Main Authors: Hyejin Choi, Jianting Sheng, Dingcheng Gao, Fuhai Li, Anna Durrans, Seongho Ryu, Sharrell B. Lee, Navneet Narula, Shahin Rafii, Olivier Elemento, Nasser K. Altorki, Stephen T.C. Wong, Vivek Mittal
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715000650

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http://www.sciencedirect.com/science/article/pii/S2211124715000650

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