Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection

Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection

Influenza A virus (IAV) is a significant cause of life-threatening lower respiratory tract infections in children. Antiviral therapy is the mainstay of treatment, but its effectiveness in this age group has been questioned. In addition, damage inflicted on the lungs by the immune response to the vir...

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Bibliographic Details
Main Authors: Bria M. Coates, Kelly L. Staricha, Nandini Ravindran, Clarissa M. Koch, Yuan Cheng, Jennifer M. Davis, Dale K. Shumaker, Karen M. Ridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
children
influenza
inflammasome
inflammation
MCC950
acute lung injury
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00782/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00782/full

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