Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Photo-transduction in cone segments (CS) is crucial for high acuity daytime vision. For ill-defined reasons, CS degenerate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which characterize geographic atrophy (GA). Our experiments confirm the loss of cone segme...

Full description

Bibliographic Details
Main Authors: Chiara M Eandi, Hugo Charles Messance, Sébastien Augustin, Elisa Dominguez, Sophie Lavalette, Valérie Forster, Shulong Justin Hu, Lourdes Siquieros, Cheryl Mae Craft, José-Alain Sahel, Ramin Tadayoni, Michel Paques, Xavier Guillonneau, Florian Sennlaub
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
age-related macular degeneration
macrophages
interleukin
subretinal space
retinitis pigmentosa
outer segments
Online Access:https://elifesciences.org/articles/16490

Internet

https://elifesciences.org/articles/16490

Similar Items