Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux

Calcium signaling has long been associated with key events of immunity, including chemotaxis, phagocytosis, and activation. However, imaging and manipulation of calcium flux in motile immune cells in live animals remain challenging. Using light-sheet microscopy for in vivo calcium imaging in zebrafi...

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Bibliographic Details
Main Authors: Rebecca W. Beerman, Molly A. Matty, Gina G. Au, Loren L. Looger, Kingshuk Roy Choudhury, Philipp J. Keller, David M. Tobin
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715013108