Augmented IFN-γ and TNF-α Induced by Probiotic Bacteria in NK Cells Mediate Differentiation of Stem-Like Tumors Leading to Inhibition of Tumor Growth and Reduction in Inflammatory Cytokine Release; Regulation by IL-10

Augmented IFN-γ and TNF-α Induced by Probiotic Bacteria in NK Cells Mediate Differentiation of Stem-Like Tumors Leading to Inhibition of Tumor Growth and Reduction in Inflammatory Cytokine Release; Regulation by IL-10

Our previous reports demonstrated that the magnitude of NK cell mediated cytotoxicity correlated directly with the stage and levels of differentiation of tumor cells. In addition, we have shown previously that activated NK cells induce growth inhibition of cancer cells through induction of different...

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Bibliographic Details
Main Authors: Vickie TamDoan Bui, Han-Ching eTseng, Phyu Ou eMaung, Anna eKozlowska, Kawal eMann, Paytsar eTopchyan, Anahid eJewett
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Monocytes
differentiation
NK
IFN-γ
probiotic bacteria
anti-IL10mAb
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00576/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00576/full

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