Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions

Abstract Low back pain (LBP), as a leading cause of disability, is a common musculoskeletal disorder that results in major social and economic burdens. Recent research has identified inflammation and related signaling pathways as important factors in the onset and progression of disc degeneration, a...

Full description

Bibliographic Details
Main Authors: Feng-Juan Lyu, Haowen Cui, Hehai Pan, Kenneth MC Cheung, Xu Cao, James C. Iatridis, Zhaomin Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-020-00125-x