Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line

<p>Abstract</p> <p>Background</p> <p>Kinesin spindle proteins (KSP) are motor proteins that play an essential role in mitotic spindle formation. <it>HsEg5</it>, a KSP, is responsible for the formation of the bipolar spindle, which is critical for proper cell...

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Bibliographic Details
Main Authors: Li Yiwei, Hussain Maha, Sarkar Sarah H, Davis David A, Sarkar Fazlul H
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/22