Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB.
In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of DNA ends by a helicase-nuclease complex such as AddAB. The activity of AddAB has been well-studied in vitro, with translocation speeds between...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-05-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC5443536?pdf=render |