FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signalingResearch in context

FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signalingResearch in context

Background: The resistance to EGF receptor (EGFR) tyrosine kinase inhibitors (TKI) is a major challenge in the treatment of non-small cell lung cancer (NSCLC). Understanding the molecular mechanisms behind resistance is therefore an important issue. Here we assessed the role of EGFR pathway substrat...

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Main Authors: Qiang Wen, Xinwei Jiao, Fei Kuang, Beibei Hou, Yajing Zhu, Wenyu Guo, Guangxin Sun, Yufeng Ba, Dandan Yu, David Wang, Faya Zhang, Hui Chao Qiao, Shuolin Wang, Shu Tang, Hailing Qiao
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419300611

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http://www.sciencedirect.com/science/article/pii/S2352396419300611

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