Concomitant experimental coinfection by Plasmodium berghei NK65-NY and Ascaris suum downregulates the Ascaris-specific immune response and potentiates Ascaris-associated lung pathology

Concomitant experimental coinfection by Plasmodium berghei NK65-NY and Ascaris suum downregulates the Ascaris-specific immune response and potentiates Ascaris-associated lung pathology

Abstract Background Ascariasis and malaria are highly prevalent parasitic diseases in tropical regions and often have overlapping endemic areas, contributing to high morbidity and mortality rates in areas with poor sanitary conditions. Several studies have previously aimed to correlate the effects o...

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Bibliographic Details
Main Authors: Flaviane Vieira-Santos, Thaís Leal-Silva, Luiza de Lima Silva Padrão, Ana Cristina Loiola Ruas, Denise Silva Nogueira, Lucas Kraemer, Fabrício Marcus Silva Oliveira, Marcelo Vidigal Caliari, Remo Castro Russo, Ricardo Toshio Fujiwara, Lilian Lacerda Bueno
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Malaria Journal
Subjects:
Plasmodium berghei NK65-NY
Ascaris suum
Coinfection
Malaria
Helminth infection
Lung inflammation
Online Access:https://doi.org/10.1186/s12936-021-03824-w

Internet

https://doi.org/10.1186/s12936-021-03824-w

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