Ionising radiation immediately impairs synaptic plasticity-associated cytoskeletal signalling pathways in HT22 cells and in mouse brain: an in vitro/in vivo comparison study.

Ionising radiation immediately impairs synaptic plasticity-associated cytoskeletal signalling pathways in HT22 cells and in mouse brain: an in vitro/in vivo comparison study.

Patients suffering from brain malignancies are treated with high-dose ionising radiation. However, this may lead to severe learning and memory impairment. Preventive treatments to minimise these side effects have not been possible due to the lack of knowledge of the involved signalling pathways and...

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Bibliographic Details
Main Authors: Stefan J Kempf, Sonja Buratovic, Christine von Toerne, Simone Moertl, Bo Stenerlöw, Stefanie M Hauck, Michael J Atkinson, Per Eriksson, Soile Tapio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110464

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https://doi.org/10.1371/journal.pone.0110464

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