Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

The cerebral cortical tissue of murine embryo and pluripotent stem cell (PSC)-derived neurons can survive in the brain and extend axons to the spinal cord. For efficient cell integration to the corticospinal tract (CST) after transplantation, the induction or selection of cortical motor neurons is i...

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Bibliographic Details
Main Authors: Jun Takahashi, Noritaka Sano, Takafumi Shimogawa, Hideya Sakaguchi, Yoshihiko Ioroi, Yoshifumi Miyawaki, Asuka Morizane, Susumu Miyamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuropilin-1
subcortical projection neuron
transplantation
corticospinal tract
cell sorting
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00123/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00123/full

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