Motor Cortex and Hippocampus Display Decreased Heme Oxygenase Activity 2 Weeks After Ventricular Fibrillation Cardiac Arrest in Rats

Motor Cortex and Hippocampus Display Decreased Heme Oxygenase Activity 2 Weeks After Ventricular Fibrillation Cardiac Arrest in Rats

Heme oxygenase (HO) and biliverdin reductase (BVR) activities are important for neuronal function and redox homeostasis. Resuscitation from cardiac arrest (CA) frequently results in neuronal injury and delayed neurodegeneration that typically affect vulnerable brain regions, primarily hippocampus (H...

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Bibliographic Details
Main Authors: Alexandra-Maria Warenits, Jasmin Hatami, Andrea Müllebner, Florian Ettl, Ursula Teubenbacher, Ingrid Anna Maria Magnet, Barbara Bauder, Andreas Janata, Ingrid Miller, Rudolf Moldzio, Anne-Margarethe Kramer, Fritz Sterz, Michael Holzer, Sandra Högler, Wolfgang Weihs, Johanna Catharina Duvigneau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Medicine
Subjects:
cardiac arrest
global cerebral ischemia
reperfusion injury
heme degradation pathway
brain regions
neurodegeneration
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00513/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00513/full

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