A method of purifying alpha-synuclein in E. coli without chromatography

A method of purifying alpha-synuclein in E. coli without chromatography

Research has implicated alpha-synuclein (aSyn) in pathological protein aggregation observed in almost all patients with Parkinson's disease and more than 50% of patients with Alzheimer's disease. An easy and inexpensive method of purifying aSyn and developing an in vitro model system of Le...

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Bibliographic Details
Main Authors: Sumaer Kamboj, Chase Harms, Lokender Kumar, Daniel Creamer, Colista West, Judith Klein-Seetharaman, Susanta K. Sarkar
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
Recombinant human alpha-synuclein
Aggregation induced by alpha-synuclein
Lewy body model system
Western blot
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402032716X

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http://www.sciencedirect.com/science/article/pii/S240584402032716X

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