Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study.

Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study.

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are both 4 microtubule binding repeat tauopathy related disorders. Clinical trials need new biomarkers to assess the effectiveness of tau-directed therapies. This study investigated the regional distribution of longitudinal diffusi...

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Bibliographic Details
Main Authors: Yu Zhang, Rudolph Walter, Peter Ng, Phi N Luong, Shubir Dutt, Hilary Heuer, Julio C Rojas-Rodriguez, Richard Tsai, Irene Litvan, Bradford C Dickerson, Maria Carmela Tartaglia, Gil Rabinovici, Bruce L Miller, Howard J Rosen, Norbert Schuff, Adam L Boxer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4911077?pdf=render

Internet

http://europepmc.org/articles/PMC4911077?pdf=render

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