Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients

Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients

Cryptococcus neoformans, an opportunistic fungal pathogen ubiquitously present in the environment, causes cryptococcal meningitis (CM) mainly in immunocompromised patients, such as AIDS patients. We aimed to identify disease-associated cryptococcal protein antigens targeted by the human humoral immu...

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Bibliographic Details
Main Authors: A. Elisabeth Gressler, Daniela Volke, Carolina Firacative, Christiane L. Schnabel, Uwe Müller, Andor Krizsan, Bianca Schulze-Richter, Matthias Brock, Frank Brombacher, Patricia Escandón, Ralf Hoffmann, Gottfried Alber
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Cryptococcus neoformans
immunoproteomics
cryptococcal meningitis
humoral immunity
human samples
fungal infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.709695/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.709695/full

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