Detection of viral RNA fragments in human iPSC cardiomyocytes following treatment with extracellular vesicles from SARS-CoV-2 coding sequence overexpressing lung epithelial cells

Detection of viral RNA fragments in human iPSC cardiomyocytes following treatment with extracellular vesicles from SARS-CoV-2 coding sequence overexpressing lung epithelial cells

Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global pandemic. The prevalence/severity of COVID-19 is higher among patients with cardiovascular risk factors. Despite the expression of angiotensin-converting enzyme 2 (ACE2...

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Bibliographic Details
Main Authors: Youjeong Kwon, Sarath Babu Nukala, Shubhi Srivastava, Hiroe Miyamoto, Nur Izzah Ismail, Jordan Jousma, Jalees Rehman, Sang-Bing Ong, Won Hee Lee, Sang-Ging Ong
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Stem Cell Research & Therapy
Subjects:
COVID-19
Extracellular vesicles
iPSCs
Stem cells
Cardiomyocytes
Online Access:https://doi.org/10.1186/s13287-020-02033-7

Internet

https://doi.org/10.1186/s13287-020-02033-7

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