Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes

A variety of biological networks can be modeled as logical or Boolean networks. However, a simplification of the reality to binary states of the nodes does not ease the difficulty of analyzing the dynamics of large, complex networks, such as signal transduction networks, due to the exponential depen...

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Bibliographic Details
Main Authors: Trevor Pentzien, Bhanwar L. Puniya, Tomáš Helikar, Mihaela T. Matache
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01185/full