Enantio and Diastereoselective Addition of Phenylacetylene to Racemic α-chloroketones

In this report, we have presented the first diastereoselective addition of phenylacetylene to chiral racemic chloroketones. The addition is controlled by the reactivity of the chloroketones that allowed the stereoselective reaction to be performed at –20 °C. Chiral racemic chloroketones are used in...

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Bibliographic Details
Main Authors: Pier Giorgio Cozzi, Diego Petruzziello, Montse Guiteras Capdevila, Enrico Emer, Silvia Alesi, Andrea Gualandi
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/6/5298/