Conformational-Dependent and Independent RNA Binding to the Fragile X Mental Retardation Protein

The interaction between the fragile X mental retardation protein (FMRP) and BC1 RNA has been the subject of controversy. We probed the parameters of RNA binding to FMRP in several ways. Nondenaturing agarose gel analysis showed that BC1 RNA transcripts produced by in vitro transcription contain a...

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Bibliographic Details
Main Authors: Xin Yan, Robert B. Denman
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2011/246127