Molecular docking simulations provide insights in the substrate binding sites and possible substrates of the ABCC6 transporter.

Molecular docking simulations provide insights in the substrate binding sites and possible substrates of the ABCC6 transporter.

The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein (ABCC6), primarily expressed in liver and kidney. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive connective tissue disease characterized by ectopic mineralizatio...

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Bibliographic Details
Main Authors: Mohammad Jakir Hosen, Abdullah Zubaer, Simrika Thapa, Bijendra Khadka, Anne De Paepe, Olivier M Vanakker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25062064/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25062064/pdf/?tool=EBI

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