ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation.

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation.

Chikungunya virus (CHIKV) is a re-emerging alphavirus that has caused significant disease in the Indian Ocean region since 2005. During this outbreak, in addition to fever, rash and arthritis, severe cases of CHIKV infection have been observed in infants. Challenging the notion that the innate immun...

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Bibliographic Details
Main Authors: Scott W Werneke, Clementine Schilte, Anjali Rohatgi, Kristen J Monte, Alain Michault, Fernando Arenzana-Seisdedos, Dana L Vanlandingham, Stephen Higgs, Arnaud Fontanet, Matthew L Albert, Deborah J Lenschow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3197620?pdf=render

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http://europepmc.org/articles/PMC3197620?pdf=render

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