Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents

Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents

Several new pyrazole, pyridine, [1,2,4]triazolo[1,5-α]pyrimidine, benzimidazo[1,2-a]pyrimidine and 1,2,4-triazolo[3,4-c][1,2,4]triazine derivatives incorporating a thiophene moiety were synthesized from (E)-ethyl 5-(3-(dimethylamino)acryloyl)-4-phenyl-2-(phenylamino)thiophene-3-carboxylate (1). The...

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Bibliographic Details
Main Authors: Yahia Nasser Mabkhot, Fatima Alatibi, Nahed Nasser E. El-Sayed, Nabila Abdelshafy Kheder, Salim S. Al-Showiman
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
thiophene
enaminone
pyrazole
pyridine
antimicrobial activity
Online Access:http://www.mdpi.com/1420-3049/21/8/1036

Internet

http://www.mdpi.com/1420-3049/21/8/1036

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